Cancer Research

In 2022, there were an estimated 20 million new cancer cases and 9.7 million deaths. The estimated number of people who were alive within 5 years following a cancer diagnosis was 53.5 million. About 1 in 5 people develop cancer in their lifetime, approximately 1 in 9 men and 1 in 12 women die from the disease.

As a knee researcher in the field of cancer  diagnosis and therapy, i have developed targeted nanomedicine and nanotheranostics for breast cancer, brain cancer, and lung cancer. In-vitro and in-vivo extensive characterization were performed by various techniques 

Morphological Analysis of developed Nanoparticles

"Chitosan nanoparticles SEM image"

SEM Image

"Chitosan nanoparticles TEM image"

TEM Image

"Chitosan nanoparticles AFM image"

AFM 2D Image

"Chitosan nanoparticles"

AFM 3D Image

Ultrasmall Magnesium nanoclusters as a in-vitro and in-vivo imaging probe

"Magnesium nanoclusters"

In vivo optical imaging of rats bearing breast tumors

"Theranostic NPs in vivo imaging"

In vivo ultrasound and photoacoustic imaging of rats bearing breast tumors

"Ultrasound and photacoustic imaging of breast tumour"

Images of the breast tumor obtained in B-mode+ PA-mode provides the information about tumour morphology, level of tumor oxygenation, deoxygenation, and tumor volume.

" breast tumour vascularity"

Images of the breast tumor obtained in Power Doppler mode provide information about tumor vascularity, angiogenesis, blood flow direction and rate 

"ICG based breast tumour imaging"

Tumor distribution of NIR sensitive dye/biomaterials loaded nanoparticles real time distribution can be observed. Images were acquired in multimode; red, blue, and green signals representing oxygenated blood, deoxygenated blood, and nanoparticles, respectively.

Live imaging of a rat breast tumour by Ultrasound/Photoacoustic imaging system, shows tumour morphology, level of tumour oxygenation.