The In Vivo Live Imaging System (Optical Imaging) enables non-invasive visualization and tracking of drug delivery and targeting in real-time within living organisms. This advanced technology provides high-resolution images, allowing researchers to study the efficacy and biodistribution of therapeutic agents dynamically. 

The In Vivo Ultrasound and Photoacoustic Imaging system allows for non-invasive visualization and tracking of biological processes in real-time within living organisms. This advanced technology combines high-resolution ultrasound with photoacoustic imaging, enabling researchers to study vascular dynamics, tissue oxygenation, and molecular targeting dynamically. 

Nuclear Magnetic Resonance Spectroscopy (NMR) is essential in chemistry for elucidating molecular structures, determining the purity of samples, and studying molecular dynamics. In polymer synthesis, NMR is used to analyze polymer composition, chain configurations, and molecular weight distributions. Additionally, it plays a crucial role in identifying and characterizing complex organic compounds, aiding in the discovery and development of new materials. 

Fourier-Transform Infrared Spectroscopy (FTIR) is widely used in chemistry for identifying functional groups and molecular structures by measuring the absorption of infrared light. In polymer synthesis, FTIR helps determine polymer composition, monitor reaction progress, and assess material properties. It is also essential for identifying and characterizing organic and inorganic compounds, ensuring quality control, and studying chemical interactions and transformations. 

X-ray Photoelectron Spectroscopy (XPS) is a powerful tool for surface analysis in materials science, providing detailed information on the elemental composition, chemical states, and electronic states of materials. In polymer synthesis, XPS is used to analyze surface modifications, monitor polymer coatings, and investigate adhesion properties. It is also crucial for characterizing thin films, catalysts, and nanomaterials, aiding in the development and optimization of advanced materials and surface treatments. 

X-ray Diffraction (XRD) is a critical technique in formulation development, providing insights into the physical state of drugs, such as their crystalline or amorphous forms. It helps determine polymorphic forms, which can significantly impact a drug's bioavailability and solubility. XRD is essential for optimizing drug formulations to enhance stability, dissolution rates, and therapeutic efficacy. 

Atomic Force Microscopy is a vital tool for characterizing nanoparticles, offering high-resolution imaging of surface topography and morphology. It provides detailed information on particle size, shape, and surface roughness, essential for optimizing nanoparticle formulations and understanding their interactions. AFM also aids in assessing the mechanical properties and stability of nanoparticles, crucial for their application in drug delivery, diagnostics, and nanotechnology. 

The X-RAD225 system is designed for small animal irradiation and targeted studies, offering the largest internal x-ray chamber available. It is ideal for large cell cultures and small animal applications. Key features include focal irradiation with automated or fixed collimators, full screen, real-time specimen viewing, and a motorized turntable with an adjustable programmable specimen shelf. The system also features integrated filter recognition, daily automated dose QA, and imaging capabilities with the OptiMAX imaging module, which allows for quick changes between imaging modalities and precise co-registration of images.

Semi-preparative High-Performance Liquid Chromatography (HPLC) with a Photodiode Array (PDA) detector is a powerful technique used for the purification and analysis of compounds in a mixture. This method combines the high-resolution separation capabilities of HPLC with the advanced detection capabilities of a PDA detector, which can simultaneously monitor multiple wavelengths. The semi-preparative scale allows for the collection of larger quantities of purified substances compared to analytical HPLC, making it ideal for applications in research and development, such as isolating bioactive compounds, synthesizing intermediates, or purifying pharmaceutical ingredients. The PDA detector enhances the method's efficiency by providing detailed spectral information, ensuring precise identification and quantification of the components in the sample.

In vivo animal handling encompasses ethical and meticulous care of laboratory animals during experiments, ensuring their welfare and reliable experimental outcomes. 

With over 7 years of experience, I am proficient in handling various laboratory animals including rats, mice, hamsters, and guinea pigs. My expertise extends to administering doses via oral, intravenous, subcutaneous, intradermal, intraperitoneal, topical, rectal, and ocular routes. I am adept at withdrawing blood samples via retroorbital route and cardiac puncture, as well as isolating vital organs such as the brain, heart, lung, liver, kidney, and spleen. My extensive experience includes conducting preclinical research experiments in pharmacokinetics, toxicology studies, and animal models for cancer (breast, lung, and colon). Additionally, I have conducted in vivo imaging studies and histopathological investigations.